Skin Rejuvenation & Wound Healing

Introduction

Skin is the largest organ in the body and has important functional and psychological significance. Aging, trauma or injury, and chronic metabolic diseases, including diabetes, often lead to alterations in skin color, texture, and barrier function. The loss of skin function leads to atrophy, infection, chronic wounds, laxity, and rhytides.

Wound healing is a complex, regulated process in which regulated collagen deposition, in response to tissue injury, results in scar formation. Its mechanisms include inflammation, fibroplasia, and scar maturation.

Sometimes cutaneous wounds do not progress to normal healing with formation of final mature scar formation but to a continuing inflammatory process, which can lead to a more aggressive carcinogenic transformation. Many chronic wounds are the result of chronic inflammation.

PEMF on Chronic Wounds & Inflammation

Studies showed PEMF as a non-invasive, non-thermal technique to rejuvenate skin. It was reported that PEMF destroy cells while simultaneously completely preserving the extracellular matrix architecture and releasing multiple growth factors locally which induce new cells and tissue growth. Certain PEMF regimens applied non-invasively were found to lead to epithelial growth, an increased in vascular supply to the skin, the formation of new microvasculature and increased collagen deposition without scarring.

Unlike contemporary physical methods that affect all tissue component, PEMF is an intervention at the cellular level, which precisely targets cell membranes through electroporation without affecting the extracellular matrix architecture. Unlike chemical interventions, PEMF is a non-invasive procedure that does not involve the application of external molecules.